As a “transportable SO3“, sulfur trioxide-amine complexes represent an interesting alternative to conventional sulfonation reagents such as chlorosulfonic acid, oleum or sulfuric acid.
SO3 amine complexes are usually easy-to-handle solids, which are mainly used in pharmaceutical synthesis for the introduction of SO3 groups. The choice of amine (base strength) controls the reactivity of the complex. Strong Lewis bases such as trimethylamine lead to a stable but less reactive complex, while dimethylformamide leads to a very reactive complex. The pyridine SO3 complex, which is the standard reagent of this product group, shows a balanced behavior with regard to reactivity and stability.
- CABB is the leading manufacturer of SO3 amine complexes.
- High-purity compounds, contain no other salts or by-products
- Mild, transportable sulfonation reagents
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Sulfur trioxide amine complexes